We've announced a new project, the Dojo Extensions for Adobe AIR. This project makes it easier to use Dojo for higher level desktop application features within AIR.

Introduction to Adobe AIR and Dojo

Adobe AIR is a new runtime by Adobe. Adobe AIR allows web applications permission to the local file system that traditional browser-based web applications do not normally receive due to security policies.

As of Dojo Toolkit 1.1.0 Beta 1, Dojo-based applications will now run successfully in Adobe AIR's secure application sandbox.